01 /What it is
Teduglutide is a 33 amino acid analog of glucagon like peptide 2 (GLP-2) with a single alanine substitution at position 2 that resists enzymatic degradation. It is sold as a prescription medicine (Gattex / Revestive) in regulated markets for short bowel syndrome and is studied as a research compound at the GLP-2 receptor.
02 /How it works
In research models, Teduglutide binds the GLP-2 receptor on enteroendocrine L cells and subepithelial myofibroblasts of the small intestine and signals through IGF-1 and other downstream mediators that drive enterocyte proliferation, villus height, and intestinal barrier integrity.
03 /What researchers explore it for
Researchers have explored Teduglutide in intestinal barrier research, in enterocyte proliferation research, and in gut hormone receptor research alongside the broader incretin family.
04 /Safety and interactions
Teduglutide is for laboratory research use only and is not for human consumption. Not medical advice. Not intended to diagnose, treat, cure, or prevent any disease.
05 /Research notes
Peptide family: incretin family, GLP-2 subclass. Frequently compared with Liraglutide, Semaglutide, and the broader GLP family. The Apothify library lists Teduglutide for encyclopedia coverage only because of its prescription status.
Related peptides
Liraglutide · Semaglutide · VIP
