01 /What it is
Macimorelin is a modified pentapeptide and the first orally active ghrelin receptor agonist with regulatory approval as a diagnostic. It is studied as a research compound at the ghrelin receptor and is sold as a prescription diagnostic (Macrilen) in regulated markets for adult growth hormone stimulation testing.
02 /How it works
In research models, Macimorelin acts at the ghrelin receptor on the anterior pituitary and triggers a single growth hormone pulse that researchers measure as the assay readout. Oral bioavailability sets it apart from the injectable ghrelin agonist family that includes Ipamorelin and the GHRP series.
03 /What researchers explore it for
Researchers have explored Macimorelin in growth hormone stimulation research, in ghrelin receptor pharmacology research, and in oral peptide bioavailability research.
04 /Safety and interactions
Macimorelin is for laboratory research use only and is not for human consumption. Not medical advice. Not intended to diagnose, treat, cure, or prevent any disease.
05 /Research notes
Peptide family: ghrelin receptor agonists, oral subclass. Frequently compared with Ipamorelin, Hexarelin, GHRP-2, and Anamorelin. The Apothify library lists Macimorelin for encyclopedia coverage only because of its prescription status.
Related peptides
Ipamorelin · GHRP-2 · Anamorelin · Hexarelin
