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Entry No. 01 · sleep stress

Endomorphin-2.

An endogenous tetrapeptide investigated in mu opioid receptor research.

Strong caution Encyclopedia only COA on file

01 /What it is

Endomorphin-2 is an endogenous tetrapeptide (Tyr-Pro-Phe-Phe-NH2) discovered alongside Endomorphin-1 in the late 1990s. It is a reference ligand in selective mu opioid receptor research.

02 /How it works

In research models, Endomorphin-2 is studied as a highly selective agonist at the mu opioid receptor. It is investigated in receptor selectivity research and in central nervous system signaling research, often in parallel with Endomorphin-1.

03 /What researchers explore it for

Researchers have explored Endomorphin-2 in mu opioid receptor research, in central signaling research, and in receptor selectivity research alongside Endomorphin-1.

04 /Safety and interactions

Research interactions of note include receptor level overlap with other endogenous opioid peptides. Endomorphin-2 is for laboratory research use only and is not for human consumption. Not medical advice. Not intended to diagnose, treat, cure, or prevent any disease.

05 /Research notes

Peptide family: endogenous opioid tetrapeptides. Frequently compared with Endomorphin-1. The Apothify library lists Endomorphin-2 for encyclopedia coverage only.

Related peptides
Endomorphin-1